周刊 1997年1月创刊(总第269期) 第11卷 第13期 2007年4月1日出版

小波变换和阻抗技术在胃动力研究中的应用***★

王 伟1,李章勇1,任超世2


Application of wavelet transform and bio-impedance technique in gastric motility
information ***★

Abstract

AIM:To investigate the method of extracting gastric motility information with wavelet transform and bio-impedance technique.

METHODS: The experiment was carried out in the Institute of Biomedical Engineering, Chongqing University of Posts and Telecommunications between July and October in 2006.①Twenty-four male volunteers aged 20-21 years were examined normal in gastric motility and were adopted in this experiment. Gastric emptying detection was performed with four probe method in bio-impedance technique after the testees were fasted for 8 hours and then drank 400 mL purified water (37 ℃).②The wavelet transform was addressed to deal with the noised body surface bio-impedance signal, in which the dbN was used to decompose the signal into multi-resolution analysis and reconstruct it on selected ones. Gastric impedance signal was obtained by eliminating the respiration impedance and blood impedance.

RESULT: All of the 24 subjects completed the test and entered the result analysis. The base impedance characteristic held the line before drinking, and stepped up after drinking, then decreased quickly, at last slow-moving stepped down. The half time of gastric empting was (8.78±1.76) minutes. The frequency scope of gastric impedance by reconstructing with the wavelet transform was ranged 2-4 counts per minute. The smooth surface was beneficial for the removal of respiration and blood impedance signal.

CONCLUSION:①Though the gastric impedance is influenced by many factors, such as gastric secretion and components of test meal, there is a corresponding relation between impedance curve and gastric perfusion by selecting non-nutrient and low-electrical conductivity solid, which provides a non-invasive method to investigate surface gastric emptying function in clinic.②Because of the identical frequency consistency of gastric impedance reconstructed by wavelet transform and gastric motility, we can use the mechanical feature to analyze and evaluate the function of gastric motility, and avoid the inaccurate judgment to the gastric function disorder through surface electrogastrography.

Wang W, Li ZY, Ren CS.Application of wavelet transform and bio-impedance technique in gastric motility information.Zhongguo Zuzhi Gongcheng Yanjiu yu Linchuang Kangfu 2007;11(13):2434-2436(China)
[www.zglckf.com/zglckf/ejournal/upfiles/07-13/13k-2434(ps).pdf]



1Institute of Biomedical Engineering, Chongqing University of Posts and Telecommunications, Chongqing 400065, China; 2Institute of Biomedical Engineering, Chinese Academy of Medical Sciences, Tianjin 300192, China

Wang Wei★, Master, Lecturer, Institute of Biomedical Engineering, Chongqing University of Posts and Telecommunications, Chongqing 400065, China
jmcar@126.com

Supported by: the National Natural Science Foundation of China, No. 60471041*; Scientific Fund of Chongqing University of Posts and Telecommunications, No. A2004-61*; Youth Science Fund of Chongqing University of Posts and Telecommunications, No. A2006-47*

Received: 2006-11-18
Accepted: 2007-03-19

摘要
目的:探索基于小波变换和阻抗技术提取胃动力信息的方法。
方法:实验于2006-07/10在重庆邮电大学生物医学信息工程研究所实验室完成。①选择胃动力正常的男性志愿者24名(年龄20~21岁),空腹8 h后喝纯净水400 mL(水温37 ℃),利用阻抗技术的四电极法进行胃排空检测。②运用小波变换方法结合Daubechies小波系对体表阻抗信号进行多分辨分析和重构,滤除呼吸阻抗和血流阻抗,进而获得胃阻抗信号。
结果:24名被试均完成测试进入结果分析。被试具有喝水前基础阻抗不变,喝水后阻抗升高,然后快速下降再缓慢下降的特点,400 mL纯净水的半排空时间为(8.78±1.76) min。利用小波变换对体表阻抗信号重构后获得的信号频率范围在2~4次/ min,表面光滑,有效去除了呼吸阻抗和血流阻抗信号。
结论:①尽管胃阻抗受到胃酸分泌、试餐成分等多种因素的影响,但选用电导率低的无营养液体仍可获得阻抗曲线和胃容积变化的对应关系,为胃排空功能研究提供一种新的体表无创检测途径。②利用小波变换重构的阻抗信号频率与健康人胃蠕动节律一致,可以对胃蠕动功能从机械特性角度进行分析和评价,从而避免了胃电信号不能准确判断胃蠕动等机械活动失常所引起的胃动力紊乱。
关键词:小波变换;生物阻抗;胃动力;胃排空

王伟,李章勇,任超世.小波变换和阻抗技术在胃动力研究中的应用[J].中国组织工程研究与临床康复,2007,11(13):2434-2436
[www.zglckf.com/zglckf/ejournal/upfiles/07-13/13k-2434(ps).pdf]


1重庆邮电大学生物医学信息工程研究所,重庆市400065;2中国医学科学院生物医学工程研究所,天津市 300192

王 伟★,男,1977年生,江西省南昌市人,回族,2004年中南民族大学毕业,硕士,讲师,主要从事医学信号检测与处理、智能医学仪器研究。
jmcar@126.com

国家自然科学基金资助项目(60471041)*;重庆邮电大学科学基金资助项目(A2004-61)*;重庆邮电大学青年科学基金资助项目(A2006-47)*

中图分类号:R319.3
文献标识码:A
文章编号:1673-8225
(2007)13-02434-03

收稿日期:2006-11-18
修回日期:2007-03-19
(06-50-11-8377/N·Y)

课题背景:胃肠动力学是一门正在迅速发展的、多学科交叉的新兴学科。目前胃动力研究与临床检测缺乏可完整了解胃运动和排空情况、且方便而有效的方法,现有的胃动力学检测方法都存在自身的缺陷,故急需开发能全面、准确了解胃运动状态的多参数同步检测方法。
应用要点:文章着重阐述了阻抗胃动力检测方法,获得了电导率低的无营养液体的排空曲线,提供了一种新的无创、快捷检测途径用于胃排空功能研究。同时利用小波变换重构了胃阻抗信号,其变化规律与胃蠕动节律一致,可以直接反映胃的机械收缩活动,从而避免了胃电信号不能准确判断胃蠕动等机械活动失常所引起的胃动力紊乱。
术语解析:生物阻抗技术是利用生物组织及器官的电学特性来提取人体生理信息的无创检测技术,它依据的原理是体内某一部分的阻抗若发生变换,其原因是体内物质或功能发生的改变恰好可反映人体生理及病理信息。



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