摘要
目的：生命早期阶段的骨密度值是预测后期骨骼状况的最佳指标。通过调查分析延吉市小学生生活习惯与骨密度关系，为提高小学生骨密度，以早期达到骨峰值量，防止日后的骨质疏松提供参考。
方法：使用青少年骨密度影响因素调查表，对2005-10/2006-01延吉市802名6~15岁朝鲜族、汉族小学生进行关于一般情况的调查以及运动史、睡眠和休养状况、饮食生活习惯等的问卷调查，并用超声波骨密度测定仪(AOS-100) 进行右脚跟骨的骨密度值测量，根据伟导速度和透过指数，计算出综合骨评价值，将有关的调查结果进行统计学处理。
结果：①调查结果一般情况：有效回答问卷率为97.9%（785名），其中朝鲜族395名，男生240名，女生155名；汉族390名，男生207名，女生183名。两民族之间的年龄及年龄构成经检验均无统计学意义。②体质量指数及骨密度：朝鲜族的体质量指数高于汉族（P < 0.05），朝鲜族的骨密度也高于汉族（P < 0.001）。③运动与骨密度关系：经常参加运动者的骨密度高于不经常参加运动者(P < 0.05)。④睡眠和休养状况与骨密度关系：睡眠质量优者骨密度高于睡眠质量差者(P < 0.05)。⑤饮食习惯对骨密度的影响：汉族经常摄取豆制品者骨密度高于不摄取者（P < 0.001）。
结论：不同民族骨密度有差异；加强体育运动、提高睡眠质量与良好的饮食习惯可增加骨密度。
关键词：骨密度；延吉市；小学生；生活习惯；组织构建

许贤姬，韩春姬，平良一彦，许松姬，荒川雅志. 延吉市小学生骨密度与生活习惯的相关性[J].中国组织工程研究与临床康复，2008，12(7):1255-1258 [www.zglckf.com/zglckf/ejournal/upfiles/08-7/7k-1255(ps).pdf]

Correlation between bone mineral density and life habits in primary school student of Yanji city

Abstract

AIM：Diabetic patients are often combined with significant increase of lipid peroxide level. Increase of free radical can severe the development of diabetic complications. Tanggukang is the clinical prescription for diabetic osteoporosis. This study was aimed to investigate the effects of Tanggukang on bone mineral density, fasting blood glucose, glycosylated hemoglobin, the activity of superoxide dismutase and the content of malondialdehyde in serum of patients with diabetic osteoporosis.
METHODS: ①139 cases of diabetic osteoporosis were enrolled at Department of Gerontology of Handan First Hospital and Department of Orthopaedics of Shexian Traditional Chinese Hospital from March 2003 to March 2006. They were divided into two groups, treatment group（n =74）(aged 60-82 years) and control group (n =65) (aged 60-85 years). Forty healthy persons doing body examination were enrolled as normal group. All the subjects signed the informed consent. ②The patients of the treatment group were treated with Tanggukang (composed of prepared rehmannia root, fructus corni, dioscorea root, caulis cynomori, tortoise plastron, salvia miltiorrhiza and szechwan lovage rhizome; water decoction, and packed by automatic decocting medicine machine). Patients of the control group were treated with Gaitianli tablet produced by Jiangsu Qidong Gaitianli Pharmaceutical Factory. All the subjects orally took conventional hypoglycemic agents, 30 days as a course. ③Changes in fasting blood sugar and glycosylated hemoglobin were determined before and after the treatment. The differences in bone mineral density, activity of superoxide dismutase and the content of malonaldehyde between the persons of normal group and the patients were measured before and after the treatment.
RESULTS: ①Compared with that before treatment, fasting blood glucose and glycosylated hemoglobin levels were obviously reduced after treatment in the two groups (P < 0.05 or P < 0.01), but no significant difference was found after the comparison between two groups (P > 0.05). ②Compared with that before treatment, bone mineral density were markedly increased after treatment in two groups (P < 0.05 or P < 0.01), and the increase of bone mineral density in the treatment group surpassed the control group（P < 0.05）. ③Compared with that before treatment, the activity of serum superoxide dismutase was significantly increased (P < 0.05 or P < 0.01) and the content of malondialdehyde was decreased (P < 0.05 or P < 0.01) in two groups. The treatment group surpassed the control group（P < 0.05）. ④Compared with normal group, bone mineral density and activity of serum superoxide dismutase were remarkably decreased, and content of malondialdehyde was distinctly increased in the treatment group and control group (P < 0.01).
CONCLUSION: Tanggukang can decrease blood sugar，and prevent the osteoporosis through regulating the free radical metabolism of patients with diabetic osteoporosis.

Zhang Y, Yu WH, Wang XL.Effects of Tanggukang on serum free radical metabolism in patients with diabetic osteoporosis.Zhongguo Zuzhi Gongcheng Yanjiu yu Linchuang Kangfu 2008;12(7):1251-1254(China)
[www.zglckf.com/zglckf/ejournal/upfiles/08-7/7k-1251(ps).pdf]